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Deciding on Surgery

Knee Replacement Alternatives: What to Try Before Surgery

Knee replacement is usually not the first treatment for knee arthritis. Exercise, weight loss, medication, injections and braces all have a place, and some smaller procedures can help selected patients. This guide summarizes what the American Academy of Orthopaedic Surgeons (AAOS) guideline says about each option, and how to tell when alternatives have stopped working for you.

Updated October 24, 2026 · 8 min read

In this guide

Key takeaways

  • Exercise and, if you are overweight, weight loss are the foundation of non-surgical care.
  • Steroid injections can give short-term relief. Gel (hyaluronic acid) injections are not recommended for routine use.
  • Arthroscopic “clean-out” surgery is not recommended for knee arthritis.
  • When pain still limits your daily life after a fair trial of these options, it is reasonable to talk to a surgeon about replacement.

Exercise and physical therapy come first

The AAOS guideline gives its strongest recommendation to exercise, whether supervised, on your own or in water. It improves pain and function, and it also helps you prepare if you do need surgery later. A physical therapist can build a program around what your knee tolerates.

If you are overweight, sustained weight loss is also recommended. Less load on the knee usually means less pain. A cane can help, too. See Weight, BMI and knee replacement →

Medication

  • Acetaminophen and anti-inflammatory medicines (NSAIDs) are recommended when they are safe for you. Ask your doctor about long-term use and side effects.
  • Opioids, including tramadol, are not recommended for knee arthritis. The guideline found they increase side effects without improving pain or function.

Injections

  • Steroid (cortisone) injections could give short-term pain relief.
  • Gel (hyaluronic acid) injections are not recommended for routine use.
  • Platelet-rich plasma (PRP) may help some people, but the evidence is limited.

If you are thinking about surgery, the timing of injections matters. Gel injections, steroid shots and knee replacement →

Braces, insoles and other options

  • Knee braces could improve function, pain and quality of life for some people.
  • Lateral wedge insoles are not recommended.
  • Acupuncture and denervation therapy may help, but the evidence is limited.
  • Glucosamine and chondroitin may help mild to moderate arthritis, but the evidence is inconsistent.

Procedures short of a full replacement

  • Arthroscopic washout or “clean-out” (lavage and debridement) is not recommended when the main problem is knee arthritis.
  • Osteotomy, an operation that realigns the bone to shift load away from the worn side, may be considered for arthritis limited to one side of the knee, usually in younger, active patients.
  • Partial knee replacement may be an option when the damage is limited to one part of the knee.

At a glance: what the guideline says

OptionAAOS guideline (2021)
ExerciseRecommended (strong)
Weight loss, if overweightRecommended (moderate)
Acetaminophen, NSAIDsRecommended when safe (strong)
Opioids, including tramadolNot recommended (strong)
Steroid injectionsShort-term relief (moderate)
Gel (hyaluronic acid) injectionsNot for routine use (moderate)
PRP, acupuncture, denervationMay help; limited evidence
BracesCould help (moderate)
Lateral wedge insolesNot recommended (strong)
Arthroscopic washoutNot recommended for arthritis (moderate)

When alternatives stop working

There is no fixed deadline, but these are signs that it may be time to talk to a surgeon:

  • Pain limits walking, stairs, sleep or work despite treatment
  • Relief from medication or injections is getting shorter or weaker
  • You have stopped doing things that matter to you
  • Your X-rays show advanced wear

For US patients, it can also help to know that Medicare’s documentation guidance for knee replacement expects a reasonable trial of non-surgical treatment, typically three months or more, along with imaging that confirms arthritis and pain that limits daily activities. Am I a candidate? →

How Dr. Kalender helps you decide

Dr. Kalender reviews your symptoms, the treatments you have already tried, your X-rays or MRI and your general health. If non-surgical care still has something to offer you, he says so. If it doesn’t, he explains what surgery would mean for you.

When non-surgical care has run its course, the first days after surgery matter most. If surgery is right for you, his own pain-free approach is designed to keep pain low from the first hours, get you walking the day after surgery and, for most patients, mean one night in the hospital. He developed it himself over about ten years.

Learn about the pain-free approach →  ·  What “bone on bone” means →

Tried everything and still in pain?

Send your X-rays or MRI and a list of the treatments you have tried. Dr. Kalender will tell you whether there is anything left to try or whether surgery makes sense now. Free, with no obligation.

Frequently asked questions

For many people, exercise, weight loss, medication and occasional injections keep symptoms manageable for years. If pain still limits your daily life after a fair trial, surgery becomes a reasonable option to discuss.

The AAOS guideline does not recommend gel (hyaluronic acid) injections for routine use. Some people report relief, so discuss the evidence with your doctor.

PRP may reduce pain for some people, but the evidence is limited, and it does not replace a worn joint.

There is no single rule. Medicare’s guidance for US coverage typically expects three months or more of documented non-surgical treatment. Your surgeon will look at how much the knee limits you.

Sources and notes

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